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Statins decrease TNF-α-induced osteoprotegerin production by endothelial cells and smooth muscle cells in vitro

✍ Scribed by E. Ben-Tal Cohen; P.J. Hohensinner; C. Kaun; G. Maurer; K. Huber; J. Wojta

Book ID
113488114
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
263 KB
Volume
73
Category
Article
ISSN
0006-2952

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## Abstract Although lipid‐lowering therapy with 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) decreases the progression of coronary artery and aortic valve calcification, the mechanism of action of these drugs to inhibit the calcification process remains unclear. In this stu