Statin therapy correlated CYP2D6 gene polymorphism and hyperlipidemia
β Scribed by Li, Juyi; Wang, Xiufang; Zhang, Zhaoqing; Zou, Jili; Chen, Yonggang; Wang, Xiong; Wu, Jinhu
- Book ID
- 124162637
- Publisher
- Informa plc
- Year
- 2013
- Tongue
- English
- Weight
- 127 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0300-7995
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Molecular genetic studies of the cytochrome P450 system enzyme CYP2D6, which hydroxylates debrisoquine, have indicated an excess of mutant alleles in large series of patients with Parkinson's disease (PD) when compared with controls. We have investigated C YP2D6 polymorphism in 91 patients with mult