Stat-1 and IRF-1: two factors in the signaling pathway of interferons related to viral load and liver damage in chronic hepatitis C (CH-C)
✍ Scribed by Elvira Molano; Esther Larrea; Patricia Boya; Elena Baixeras; Iosu Sola; Miguel-Angel Munoz-Navas; MaPilar Civeira; Jesús Prieto
- Book ID
- 118565722
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 114 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The nonstructural 5B (NS5B) protein of hepatitis C virus possesses RNA‐dependent RNA polymerase activity and plays an essential role in viral replication. The mutations in NS5B were determined and the correlation with viral load and response to interferon (IFN) were assessed. The entire
In patients with chronic hepatitis C, the influence of the genetic heterogeneity of the hepatitis C virus (HCV) on the progression of liver disease and on the responsiveness to interferon therapy is a matter of controversy. In this study we evaluated the genetic complexity of HCV by singlestrand con