Staphylococcal nuclease reviewed: A prototypic study in contemporary enzymology

✍ Scribed by Philip W. Tucker; Edward E. Hazen; F. Albert Cotton

• Book ID: 104669307
• Publisher: Springer
• Year: 1979
• Tongue: English
• Weight: 965 KB
• Volume: 23
• Category: Article
• ISSN: 0300-8177
• DOI: 10.1007/bf00219452

✦ Synopsis

This is the last in a series of four articles in which the chemical, enzymological and crystallographic work on Ribonucleate (deoxyribonucleate)-3'-nucleotidohydrolase, EC 3.1.4.4 (staphylococcal nuclease, micrococcal nuclease) will be reviewed and correlated. This article discusses the use of the nuclease as a model system for the study of the mechanisms and energetics of the folding-unfolding reaction in proteins and for the study of the interrelationships between amino acid sequence and three-dimensional structure.