STAP-8: A subroutine package for statistical online analysis of simultaneous neuronal spike trains
✍ Scribed by Urs R. Wyss
- Publisher
- Elsevier Science
- Year
- 1970
- Weight
- 627 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0010-468X
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✦ Synopsis
This paper presents a computer program including a subroutine package for the statistical analysis of neuronal spike trains. Extended use was made of an information display concept, on-line control via teletype intercommunication and the use of a versatile laboratory peripheral, including, among other features, Schmitt-Trigger inputs, multiplexed analog-digital converters, and a variable RC-clock, The software, written exclusively in the system's specific symbolic assembler language, was compiled and tested on a LAB-8 System of DEC**, extended with the Arithmetic Element MP8/1, the Mini-Disk DF32, and the Tektronix Type 601 Storage Oscilloscope, and is available as an assembly listing together with the binary paper tape.
From the neuronal spike trains recorded simultaneously by two Schmitt-Trigger inputs, interspike intervals are counted by the RC-clock counting chain and translated into 12-bit positive integers. These interval data files stored on the disk are available to eight different analysis programs: Interval histogram, autocorrelogram, cumulative distribution function, conditioned probability density, serial correlogram, cross-correlogram, post-stimulus time histogram, and time interval sequence. The results are given as a function or histogram display, or may be punched on paper tape for further analysis.
Neurophy siology
Spiketrain analysis Small computer Stochastic point process 1. COMPUTATIONAL METHODS 1.1. STAP-8 does not investigate a new kind of statistical procedure for spike train analysis but rather was designed to give the experimenter an easy-to-control library of well known statistical calculation and display programs which may help to get an instant overview of microelectrode data recording during the experiment. There exist already several off-line analysis programs, e.g. from Lewis [7] for the IBM 7094 and IBM 360 systems, and from Perkel for the IBM 7044