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Stannous ion quantitation in99mTc-radiopharmaceutical kits

✍ Scribed by L. R. Chervu; B. Vallabhajosyula; J. Mani; S. B. Chun; M. D. Blaufox

Publisher
Springer
Year
1982
Tongue
English
Weight
210 KB
Volume
7
Category
Article
ISSN
0340-6997

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✦ Synopsis

A simple and inexpensive method for the estimation of stannous ion, Sn (II), in radiopharmaceutical kits is described. The method used is a potentiometric titration of Sn (II) in 1 N HCI medium, using potassium iodate as the oxidizing agent in an atmosphere of nitrogen. The apparatus includes pH meter, a platinum electrode, and a simple titration cell. Several commonly used radiopharmaceutical kits were analyzed for their Sn (II) content using this method. These studies indicate that the procedure can be used, as a routine quantitative test for the Sn (II) content of various 99mTc-labeled radiopharmaceuticals.

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