Two subpopulations of small and large leukemia cells and binucleated cells were present in the bone marrow of a 10-year-old girl with acute lymphoblastic leukemia (ALL). Cytogenetic studies showed some cells with a karyotype of 34,X,-X,-2,-3,-4,-5,-7,-9, -13,-15,-16,-17,-20, and others with a karyot
✦ LIBER ✦
Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible
✍ Scribed by Michael Norbert Dworzak; Giuseppe Gaipa; Richard Ratei; Marinella Veltroni; Angela Schumich; Oscar Maglia; Leonid Karawajew; Allessandra Benetello; Ulrike Pötschger; Zvenyslava Husak; Helmut Gadner; Andrea Biondi; Wolf-Dieter Ludwig; Giuseppe Basso
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 614 KB
- Volume
- 74B
- Category
- Article
- ISSN
- 1552-4949
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Background. The prevalence, in unselected patients with acute lymphoblastic leukaemia (ALL), of clonal rearrangements suitable for minimal residual disease (MRD) studies has not been formally investigated. Procedure. This was a prospective, demographic study of the frequency of molecular markers of