Very short heat shocks are administered to carefully staged early embryos of Drosophila melanogaster, and the effects on protein synthesis pattern investigated. A shock as short as 2 min will induce the heat shock response (reduction of normal protein synthesis, increased synthesis of the heat shock
Stage dependent synthesis of heat shock induced proteins in early embryos of Drosophila melanogaster
β Scribed by Dura, Jean-Maurice
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 932 KB
- Volume
- 184
- Category
- Article
- ISSN
- 0026-8925
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β¦ Synopsis
The synthesis of heat shock proteins (hsp) has been examined during the early embryogenesis of Drosophila melanogaster. Normal protein synthesis stops after heat shock at all developmental stages, while hsp synthesis is induced only after treatment at blastoderm and later stages. The small hsps continue to be synthesised after heat shock for a longer period than the larger ones. Heat shocks at 35 Β° C, 37 Β° C and 40 Β° C were compared for their effect on hsp synthesis and the effect of heat shock on the normal course of development was analysed.
π SIMILAR VOLUMES
Heat shock of 37 degrees C applied to Drosophila embryos at blastoderm stage induces phenocopies of some dominant mutants of the bithorax complex. Heat shock might shut down functions of cis regulator genes involved in embryonic pattern formation.
The effect of inhibitors of protein synthesis on RNA synthesis was investigated before and during heat shock. The results indicate that proteins specifically made following heat shock might be required for the resumption, after heat shock, of the synthesis of the RNA normally made at 25 degrees C. I
## Abstract We explored the reproductive toxicity of argemone oil and its principal alkaloid fraction in transgenic __Drosophila melanogaster__ (__hsp70βlacZ__) __Bg^9^__. The toxicity of argemone oil has been attributed to two of its physiologically active benzophenanthridine alkaloids, sanguinari