We have examined the effects of the synthetic matrix metalloproteinase inhibitor, batimastat (BB-94) and the angiotensin-converting enzyme inhibitor, captopril, on metalloproteinase activity of murine Lewis-lung-carcinoma cells (3LL) in vitro, and on local growth and lung metastasis of the same tumo
✦ LIBER ✦
Stable knockdown of TPPP3 by RNA interference in Lewis lung carcinoma cell inhibits tumor growth and metastasis
✍ Scribed by Wenbai Zhou; Jiada Li; Xuanchun Wang; Renming Hu
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 643 KB
- Volume
- 343
- Category
- Article
- ISSN
- 0300-8177
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## Abstract Antibiotic forms of tetracycline exhibit antitumor activity in some tumor models. However, their low __in vivo__ efficacy and associated morbidity limit their long‐term application in cancer therapy. This report appraises the efficacy of doxycycline (DC) and non‐antimicrobial, chemicall