Stable and monodisperse lipoplex formulations for gene delivery
β Scribed by Zelphati, O; Nguyen, C; Ferrari, M; Felgner, J; Tsai, Y; Felgner, P L
- Book ID
- 110038259
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 519 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0969-7128
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π SIMILAR VOLUMES
Gene therapy has emerged as a promising approach for the treatment or prevention of acquired and genetic diseases. At the present time, major somatic gene transfer approaches employ either viral or non-viral vectors. Viral vectors show high gene transfer efficiency, but are deficient in several area
The efficiency of biomaterial-based gene delivery is determined by the interaction of the material and the vector. For lipoplexes, surface immobilization has been used to transfect cells for applications such as cell arrays and model tissue formation through patterned transfection. Further increases