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Stabilizing the Boat Conformation of Cyclohexane Rings

✍ Scribed by Dasgupta, Siddharth; Tang, Yongchun; Moldowan, J. Michael; Carlson, Robert M. K.; Goddard, William A.


Book ID
121289482
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
237 KB
Volume
117
Category
Article
ISSN
0002-7863

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## Abstract An analysis of the conformational preferences of two maleimide substituted cyclohexane derivatives proposed as scaffolds for HIV‐1 fusion inhibitors is presented. Hybrid Low Mode‐Monte Carlo (1:1) conformational searches using seven different force fields were performed in combination w