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Stabilizing insulin-like growth factor-I in poly(d,l-lactide-co-glycolide) microspheres

✍ Scribed by Lorenz Meinel; Oscar E. Illi; Jürgen Zapf; Marco Malfanti; Hans Peter Merkle; Bruno Gander


Book ID
114160771
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
675 KB
Volume
70
Category
Article
ISSN
0168-3659

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Ketotifen (KT) was encapsulated into poly(D,L-lactide) (PLA) and poly(D,Llactide-co-glycolide) (PLGA 50/50) by spray-drying to investigate the use of biodegradable drug-loaded microspheres as delivery systems in the intraperitoneal cavity. Ketotifen stability was evaluated by HPLC, and degradation w