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Stabilized carbanions by alkyllithium-induced decarboxylation of non-enolizable carboxylic acids. An anionic equivalent to the hunsdiecker reaction

✍ Scribed by John P. Gilday; Leo A. Paquette


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
191 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


Intermediate dianions formed by nucleophilic attack of methyllithium on a-phenyl or a-phenylthio carboxylate salts fragment in highly coordinating solvents to produce stabilized carbanions.

Once formed, these anions may be conveniently functionalized with various electrophilic reagents.