β Scribed by James Ballinger; Margaret Der; Barry Bowen
No coin nor oath required. For personal study only.
The in vitro oxidation of 99mTc-labelled bone-scanning agents with the release of free sodium 99mTc-pertechnetate results in poor skeletal images. Gentisic acid (2,5-dihydroxy-benzoic acid), which has been used as an antioxidant to stabilize HEDP and HMDP kits, has now been shown to be an effective stabilizer for 99mTc-Pyrophosphate Injection and doses not compete for 99mTc-label.
π SIMILAR VOLUMES
Renal ischemia injury was induced by transient 30-min occlusion of the main artery in five rabbits and by transient 60-min occlusion in four rabbits. The vessels to the contralateral kidneys were ligated in all nine animals and in six additional control rabbits. Renal blood flow was restored immedia
The biodistribution of four 99mTc labelled MDP preparations with different stabilizing agents were studied in young rats. The study was performed with MDP gentisic acid as a standard versus MDP ascorbic acid and MDP PABA. All results were tested statistically by the Wilcoxon-van-Eltern test.