Stabilization of the ribonuclease S-pept
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Jeffrey W. Nelson; Neville R. Kallenbach
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Article
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1986
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John Wiley and Sons
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English
⚖ 729 KB
The effects of trifluoroethanol (TFE) on the stability of the alpha-helix formed by ribonuclease S-peptide, residues 1-19 of ribonuclease A, were studied by measuring circular dichroism as a function of TFE concentration, pH, and temperature. The S-peptide forms an unusually stable alpha-helix, whic