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Stabilization of the fibrous structure of an α-helix-forming peptide by sequence reversal

✍ Scribed by Shuichi Kojima; Yukino Kuriki; Kazumori Yazaki; Kin-ichiro Miura


Book ID
116290412
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
397 KB
Volume
331
Category
Article
ISSN
0006-291X

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Stabilization of the ribonuclease S-pept
✍ Jeffrey W. Nelson; Neville R. Kallenbach 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 729 KB

The effects of trifluoroethanol (TFE) on the stability of the alpha-helix formed by ribonuclease S-peptide, residues 1-19 of ribonuclease A, were studied by measuring circular dichroism as a function of TFE concentration, pH, and temperature. The S-peptide forms an unusually stable alpha-helix, whic