Stabilization of Pores in Lipid Bilayers by Anisotropic Inclusions
✍ Scribed by Fošnarič, Miha; Kralj-Iglič, Veronika; Bohinc, Klemen; Iglič, Aleš; May, Sylvio
- Book ID
- 127277880
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 104 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0022-3654
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Nodularin (NODLN), a cyclic pentapeptide hepatotoxin from the cyanobacterium Nodularia spumigena, induces pores in bilayers of diphytanoyl lecithin (DPhL) and in locust muscle membrane. NODLN increases the surface pressure of a DPhL monolayer; except when the surface pressure of the monolayer is hig
## Abstract A theoretical model of a two-component bilayer membrane was used in order to describe the influence of anisotropic membrane inclusions on shapes of membrane daughter micro and nano vesicles. It was shown that for weakly anisotropic inclusions the stable vesicle shapes are only slightly