Stabilization of Peptide Microstructures by Coordination of Metal Ions
โ Scribed by Markus Albrecht
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
A kinetic study of the reactivity in the cleavage of pnitrophenyl acetate of a series of 2-pyridineoximes, 1ฯช4, and their complexes with Ni II , Zn II and Cu II is reported. Complexation of the oximic ligands leads to a remarkable increase in the acidity of the oximic group, following the order Cu I
Recent studies on Cu(I1) complexes with proline containing peptides have shown that the proline residue may act as a 'break-point' in the peptide sequence unless it is on a N-terminal position [ 1,3]. The lysine residue, on the other hand, may in specific cases bind the metal ion via its lateral NH