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Stabilization of Methylene Radicals by Cob(II)alamin in Coenzyme B12 Dependent Mutases.

✍ Scribed by Wolfgang Buckel; Christoph Kratky; Bernard T. Golding


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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Dedicated to Professor Albert Eschenmoser on the occasion of his 75th birthday 2-Methylideneglutarate mutase is an adenosylcobalamin (coenzyme B 12 )-dependent enzyme that catalyses the equilibration of 2-methylideneglutarate with (R)-3-methylitaconate. This reaction is believed to occur via protein