𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer

✍ Scribed by Marlene Carmo; Ana Alves; Ana Filipa Rodrigues; Ana Sofia Coroadinha; Manuel Jose Teixeira Carrondo; Paula Marques Alves; Pedro Estilita Cruz


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
328 KB
Volume
11
Category
Article
ISSN
1099-498X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Production of lentiviral vectors by tran
✍ Seraphin Kuate; Daniela Stefanou; Dennis Hoffmann; Oliver Wildner; Klaus Überla πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 352 KB

## Abstract ## Background The potential of lentiviral vectors for clinical gene therapy has not yet been evaluated. One of the reasons is the cytotoxicity of lentiviral packaging genes which makes the generation of stable producer cell lines difficult. Therefore, a novel packaging system for lenti

Development of photoreceptor-specific pr
✍ Marjorie Nicoud; Jian Kong; Sharifah Iqball; On Kan; Stuart Naylor; Peter Gouras πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 281 KB

## Abstract ## Background We wanted to investigate the ability of recombinant equine infectious anemia virus (EIAV) vectors to transduce photoreceptor cells by developing a series of photoreceptor‐specific promoters that drive strong gene expression in photoreceptor cells. ## Methods Promoter fr

Gene transfer to the spinal cord neural
✍ W. T. J. Hendriks; R. Eggers; J. Verhaagen; G. J. Boer πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 531 KB

## Abstract Viral vector–mediated overexpression of neurotrophins in cells constituting the neural scar may represent a powerful approach to rendering scar tissue of a central nervous system (CNS) lesion permissive for neuronal regrowth. In this study a lentiviral vector encoding green fluorescent

From retroviral vector production to gen
✍ M. Carmo; A. Panet; M. J. T. Carrondo; P. M. Alves; P. E. Cruz πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 313 KB

## Abstract ## Background The loss of gene transfer capacity in retroviral vectors constitutes a major disadvantage in the development of retroviral vectors for gene therapy applications. In the present work the loss of a vector's capacity to perform reverse transcription was studied as a possible