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Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma

✍ Scribed by Drakos, E; Atsaves, V; Li, J; Leventaki, V; Andreeff, M; Medeiros, L J; Rassidakis, G Z


Book ID
109886720
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
397 KB
Volume
23
Category
Article
ISSN
0887-6924

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✍ Jane L. Watson; Anna Greenshields; Richard Hill; Ashley Hilchie; Patrick W. Lee; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 389 KB

New cytotoxic agents are urgently needed for the treatment of advanced ovarian cancer because of the poor long-term response of this disease to conventional chemotherapy. Curcumin, obtained from the rhizome of Curcuma longa, has potent anticancer activity; however, the mechanism of curcumin-induced