## Abstract Using BrdUβlabeling and acridine orange staining, the behavior of Xβchromosome replication was studied in 28 XXX and 19 XXY digynous mouse triploids. In some of these the paternal and maternal X chromosome could by cytologically distinguished. Such embryos were obtained by mating chromo
Stability of X chromosome differentiation in mouse embryos
β Scribed by Nobuo Takagi
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 540 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0340-6717
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β¦ Synopsis
By means of a double labeling method with H3-thymidine and 5-bromodeoxyuridine, it was found that the X chromosome showed no sign of change from an allocyclic to an isocyclic state, or vice vers in 6.5- and 7.5-day mouse embryos. Thus, reversal of allocycly may not account for the predominance of cells with the paternally derived X chromosome inactive in the yolk sac and the chorion of the mouse embryo.
π SIMILAR VOLUMES
Isonicotinic acid hydrazide (INH) were given by peroral intubation to pregnant mice of strain C57BL/6Ffm on day 9 of pregnancy, INH was given in the following doses: 0, 5, 25, and 125 mg/kg solved in physiological saline. Cytogenetic analysis of homogenized embryos 6, 12, 24, and 48 h, resp., after