## Abstract High‐mobility group box–1 (HMGB1) was originally identified as a ubiquitously expressed, abundant nonhistone DNA‐binding protein. Recently, it was found to act as a cytokine‐like mediator of delayed endotoxin lethality and of acute lung injury. Previously, we reported that HMGB1 is mass
Stability of the maize chromosomal high-mobility-group proteins, HMGa and HMGb,in vivo
✍ Scribed by Klaus D. Grasser; Winfried Hetz; Günter Feix
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 411 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0167-4412
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✦ Synopsis
Chromosomal non-histone high-mobility-group (HMG) proteins represent essential components of eukaryotic chromatin and have also been isolated from a variety of plants. In maize, studies on structure and function of the two larger of the four major H M G proteins have recently been performed and are now extended by analysis of their in vivo stability using pulse-chase experiments in a cell suspension culture. The half-life of the analyzed H M G a and H M G b proteins was found to be 65 h or more than 78 h, respectively.
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