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Stability of the glycoproteins from a primary human pancreatic carcinoma during cell culture and in vivo passage in nude mice

✍ Scribed by Koch, G; Smith, M J; Grant, A G; Hermon-Taylor, J


Book ID
109835498
Publisher
Nature Publishing Group
Year
1983
Tongue
English
Weight
947 KB
Volume
47
Category
Article
ISSN
0007-0920

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We have examined the anti-tumor effect in nude mice caused by human pancreatic cancer cells (AsPC-1) modified to secrete IL-2 or IL-4. Loss of tumorigenicity of cytokineproducing, but not wild-type, cells was observed despite their unaltered in vitro proliferation rates; and these anti-tumor effects