✍ Scribed by Vinard, Elisabeth ;Eloy, Rosy ;Descotes, Jacques ;Brudon, Jean Robert ;Guidicelli, Henri ;Magne, Jean Luc ;Patra, Philippe ;Berruet, R�gis ;Huc, Alain ;Chauchard, Jacques
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Twenty-two cases of vascular graft failures (thrombosis, pseudoaneurysm, dilation, infection) were investigated by means of physicochemical, histological, and ultrastructural studies. A general decrease of mechanical resistance to stress of the prostheses was observed. Its magnitude ranged from 2 to 75% of the values of identical virgin prostheses and there was no relation with the duration of implantation. In addition to the breakage of yarn filaments (SEM), migration of fiber debris (histology) was observed in 7 cases. The structure of the polyester molecule had evolved after implantation. A decrease of crystallinity (x-ray diffraction and differential scanning calorimetry) was noted. These observations raise the question of the established stability of vascular prostheses and emphasize the need for further investigations in human graft retrieval programs.
MATERIAL AND METHOD
Virgin grafts were commercial products identical to those sold for human implantation. Explanted specimens were obtained through the collaboration
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