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Stability of Natamycin and Its Cyclodextrin Inclusion Complexes in Aqueous Solution

✍ Scribed by Koontz, John L.; Marcy, Joseph E.; Barbeau, William E.; Duncan, Susan E.

Book ID
111879577
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
68 KB
Volume
51
Category
Article
ISSN
0021-8561

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✍ Erdal Cevher; Demet Şensoy; Mire Zloh; LΓΌtfiye MΓΌlazΔ±moğlu πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 419 KB

Novel formulations of vaginal bioadhesive tablets were prepared where the natamycin was complexed with gamma-cyclodextrin (NT-gamma CyD) to increase the solubility and stability of NT in aqueous solutions and reduce the side effects of the drug without decreasing antimycotic activity. Favourable int