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Stability of Membrane Proteins: Relevance for the Selection of Appropriate Methods for High-Resolution Structure Determinations

✍ Scribed by Jurg P. Rosenbusch


Book ID
115634271
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
108 KB
Volume
136
Category
Article
ISSN
1047-8477

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Three different methods are currently used for the study of high-resolution structures of membrane proteins: X-ray crystallography, electron crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Thus far, all methods combined have yielded a rather modest number of crystal structures th

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Numerical simulation of fluid-structure interactions has typically been done using partitioned solution methods. However, partitioned methods are inherently non-conservative and generally numerically unstable. The deficiencies of partitioned methods have motivated the investigation of monolithic sol