In a study of 2923 normal pregnancies and 203 pregnancies affected by trisomy 21 we have shown a signi®cant difference in the median MoM of the markers: fetal nuchal translucency, maternal serum free b-hCG and PAPP-A in the presence of a female fetus compared with a male fetus. For maternal serum fr
Stability of free β-subunit in routine practice for trisomy 21 maternal serum screening
✍ Scribed by Françoise Muller; Christophe Doche; Sandrine Ngo; Sébastien Faïna; Marie-Antoinette Charvin; Maryneige Rebiffé; Valérie Taguel; Bernard Dingeon
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 171 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0197-3851
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In a study of 50 cases of trisomy 18 compared with 947 controls we have found the median multiple of the median (MoM) of maternal serum free human chorionic gonadotrophin to be significantly decreased (0.281 MoM) in samples collected between the 10th and 14th week of gestation. Similarly, maternal s
In 42 cases of trisomy 13 at 10±14 weeks of gestation, compared with 947 controls, the median multiple of the median (MoM) of maternal serum free b-human chorionic gonadotrophin (b-hCG) and pregnancy associated plasma protein A (PAPP-A) was signi®cantly decreased (0.506 MoM and 0.248 MoM respectivel