Molecular-weight-dependent pharmacokinet
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Reza Mehvar; Tracy L. Shepard
📂
Article
📅
1992
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John Wiley and Sons
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English
⚖ 616 KB
The dependency of the pharmacokinetics of fluorescein-labeled dextrans on M(r) was studied in adult Sprague-Dawley rats. Single intravenous doses (5 mg/kg) of the dextrans with M(r) of 4000, 20,000, 40,000, 70,000, or 150,000 and single oral doses (50 mg/kg) of the dextrans with M(r) of 4000, 20,000