## Background: Exfoliated cervical cell specimens collected in preservcyt, a methanol-based medium used in thinprep liquid-based cytology, have been archived in epidemiologic studies. however, long-term dna stability and cytologic stability of these biospecimens have not been evaluated. ## Methods
Stability of archived liquid-based cytologic specimens
โ Scribed by Castle, Philip E. ;Hildesheim, Allan ;Schiffman, Mark ;Gaydos, Charlotte A. ;Cullen, Allison ;Herrero, Rolando ;Bratti, M. Concepcion ;Freer, Enrique
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 74 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
In his letter, he emphasizes the fact that no reliable cytomorphologic methods exist for the differential diagnosis of thyroidal lesions with follicular architecture, when features specific for papillary thyroid carcinoma are lacking. However, our impression of his subsequent comments is that they reflect
๐ SIMILAR VOLUMES
See related editorial on pages 187-90, this issue.
## Background: Cervical carcinoma is a common malignancy among women worldwide, and its pathogenesis is related causally to human papillomavirus infection. the progression from precursor squamous intraepithelial lesions to cervical carcinoma requires additional genetic and epigenetic alterations th