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Stability of 5-aminolevulinic acid in aqueous solution

โœ Scribed by B Elfsson; I Wallin; S Eksborg; K Rudaeus; A.M Ros; H Ehrsson


Book ID
114302737
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
79 KB
Volume
7
Category
Article
ISSN
0928-0987

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Stability of 5-aminolevulinic acid in no
โœ Paul A. McCarron; Ryan F. Donnelly; Gavin P. Andrews; A. David Woolfson ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 211 KB

Aminolevulinic acid (ALA) stability within topical formulations intended for photodynamic therapy (PDT) is poor due to dimerisation to pyrazine-2,5-dipropionic acid (PY). Most strategies to improve stability use low pH vehicles, which can cause cutaneous irritancy. To overcome this problem, a novel