## Abstract Metal nanoparticle constructs of particles of different sizes and materials were prepared, using DNA as connecting element. Therefore, gold and silver nanoparticles were functionalized with complementary DNA sequences that enabled a controlled coupling. The well‐established system based
✦ LIBER ✦
Stability and hybridization-driven aggregation of silver nanoparticle–oligonucleotide conjugates
✍ Scribed by Vidal Jr., Bernardo C.; Deivaraj, Theivanayagam C.; Yang, Jun; Too, Heng-Phon; Chow, Gan-Moog; Gan, Leong M.; Lee, Jim Y.
- Book ID
- 111643367
- Publisher
- Royal Society of Chemistry
- Year
- 2005
- Tongue
- English
- Weight
- 598 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1144-0546
- DOI
- 10.1039/b417683a
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## Abstract Peptide nucleic acids (PNA) and PNA–DNA chimeras carrying thiol groups were used for surface functionalization of Au nanoparticles. Conjugation of PNA to citrate‐stabilized Au nanoparticles destabilized the nanoparticles causing them to precipitate. Addition of a tail of glutamic acid t