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Stability and dissociation of the DNA complexes with distamycin A and netropsin in the presence of organic solvents, urea and high salt concentration

โœ Scribed by Christoph Zimmer; Gerhard Luck


Book ID
115744890
Publisher
Elsevier Science
Year
1972
Weight
570 KB
Volume
287
Category
Article
ISSN
0005-2787

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Distamycin A affects the stability of NF
โœ Robert E. Speight; Darren J. Hart; Jonathan M. Blackburn ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 155 KB

## Abstract The effect of two different DNA minor groove binding molecules, Hoechst 33258 and distamycin A, on the binding kinetics of NFโ€ฮบB p50 to three different specific DNA sequences was studied at various salt concentrations. Distamycin A was shown to significantly increase the dissociation ra