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Stability and activity of chymotrypsin immobilized on magnetic nanogels covered with carboxyl groups

✍ Scribed by Jun Hong; Jin Huang; Shunying Liu; Jiahui Yu; Shufang Luo


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
167 KB
Volume
111
Category
Article
ISSN
0021-8995

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## Abstract Thiol groups were introduced to unfractionated heparin (UFH) and end‐aminated heparin (HepNH~2~) by reaction with 2‐iminothiolane under conditions favoring selective modification of terminal over primary amines. End‐thiolated heparin retained anticoagulant activity as shown by the activ