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Sry Gene Expression In The Ovotestes Of XX True Hermaphrodites

✍ Scribed by Ortenberg, Joseph; Oddoux, Carole; Craver, Randall; Mcelreavey, Ken; Salas-Cortes, L.; Guillen-Navarro, Encarnacion; Ostrer, Harry; Sarafoglou, Kyriakie

Book ID
122506859
Publisher
Lippincott Williams and Wilkins
Year
2002
Tongue
English
Weight
168 KB
Volume
167
Category
Article
ISSN
0022-5347

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## Yp -specific sequences, including the testicular determinant gene SRY, have been detected and located in a 46,XX true hermaphrodite individual, using PCR amplification and fluorescent in situ hybridization (FISH). Among different Y chromosome loci tested, it was only possible to detect Yp sequen

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A total of 30 cases of 46,XX true hermaphroditism was analysed for Y-DNA sequences including the recently cloned gene for male testis-determination SRY. In 3 cases, a portion of the Y chromosome including SRY was present and, in 2 cases, was localised, to Xp22 by in situ hybridisation. Since previou