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Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site

✍ Scribed by Wallez, Y; Cand, F; Cruzalegui, F; Wernstedt, C; Souchelnytskyi, S; Vilgrain, I; Huber, P


Book ID
110071862
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
310 KB
Volume
26
Category
Article
ISSN
0950-9232

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## Abstract ## Purpose To investigate the heterogeneity in the angiogenic response of a human breast cancer xenograft to a novel vascular endothelial growth factor (VEGF)‐receptor tyrosine kinase inhibitor, AG‐013736, using dynamic contrast‐enhanced MR imaging (DCE‐MRI). ## Materials and Methods