Spread of nontuberculous mycobacteria from 1993 to 2006 in Koreans
✍ Scribed by Sung Weon Ryoo; Sonya Shin; Myung-shup Shim; Yoon-Sung Park; Woo Jin Lew; Sue-Nie Park; Young Kil Park; Seongman Kang
- Book ID
- 102311286
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 197 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0887-8013
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✦ Synopsis
Abstract
In Korea, the prevalence of nontuberculous mycobacterial (NTM) pulmonary disease has risen, observed primarily in immunocompetent patients with or without preexisting lung disease. The purpose of this study was to determine the frequency of various species of NTM isolates from respiratory specimens in a single institution over a 14‐year period in Korea. All samples referred to our reference laboratory over a 14‐year period in Korea were analyzed. From 1993 to 2000 our laboratory used conventional NTM identification methods, and from 2001 we adapted PCR‐restrictionfragment length polymorphism analysis(PRA). A total of 17,915 isolates were collected from 1993 to 2006. The most frequently isolated organisms were M. avium complex (n=11,705, 65%), M. abscessus (n=2,076, 11.59%), M. fortuitum complex (n=1,279, 7.14%). M. chelonae complex (n=1,134, 6.33%), M. kansasii (n=762, 4.25%), M. szulgai (n=139, 0.78%), M. celatum (n=87, 0.49%), M. scrofulaceum (n=18, 0.10%) and M. marium (n=11, 0.06%). J. Clin. Lab. Anal. 22:415–420, 2008. © 2008 Wiley‐Liss, Inc.