## Abstract ## Background Pulmonary delivery of gene therapy offers the potential for the treatment of a range of lung conditions, including cystic fibrosis, asthma and lung cancer. Sprayβdrying may be used to prepare dry powders for inhalation; however, aerosolisation of such powders is limited,
β¦ LIBER β¦
Spray-dried respirable powders containing bacteriophages for the treatment of pulmonary infections
β Scribed by Sadaf Matinkhoo; Karlene H. Lynch; Jonathan J. Dennis; Warren H. Finlay; Reinhard Vehring
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 342 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0022-3549
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## Abstract ## Background Pulmonary gene therapy requires aerosolisation of the gene vectors to the target region of the lower respiratory tract. Pulmonary absorption enhancers have been shown to improve the penetration of pharmaceutically active ingredients in the airway. In this study, we invest