Paternal age and sporadic neurofibromato
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Greta R. Bunin; Michael Needle; Vincent M. Riccardi
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Article
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1997
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John Wiley and Sons
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English
⚖ 34 KB
Sporadic neurofibromatosis 1 (NF1) occurs in the absence of a family history of the disease and usually results from a new mutation in the germ cell of one of the parents, most commonly the father. Older paternal age may increase the risk for a new germinal NF1 mutation, but the results of studies t