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Sporadic rapid-onset dystonia–parkinsonism syndrome: Failure of bilateral pallidal stimulation

✍ Scribed by Angela Deutschländer; Friedrich Asmus; Thomas Gasser; Ulrich Steude; Kai Bötzel

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 61 KB
Volume: 20
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.20296

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✦ Synopsis

Abstract

We report on a woman who had a severe sporadic nonprogressive dystonia–parkinsonism syndrome with rapid onset of symptoms at age 21. Secondary causes for dystonia were ruled out. No response to levodopa/carbidopa was seen. The patient fulfilled all diagnostic criteria of rapid‐onset dystonia–parkinsonism, except for autosomal‐dominant inheritance. Bilateral deep brain stimulation of the globus pallidus failed to alleviate her symptoms. © 2004 Movement Disorder Society

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