Spontaneously Opening GABAAChannels in CA1 Pyramidal Neurones of Rat Hippocampus
β Scribed by B. Birnir; A.B. Everitt; M.S.F. Lim; P.W. Gage
- Book ID
- 105926980
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 587 KB
- Volume
- 174
- Category
- Article
- ISSN
- 0022-2631
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The induction threshold, and the magnitude and direction of changes in synaptic plasticity may depend on the previous history of neuronal activity. This phenomenon, termed βmetaplasticity,β could play an important role in integration processes by coordinating the modulation of synapses.
Intracellular recordings were made from hippocampal CA1 pyramidal cells in slices where the CA3/CA4 region had been lesioned using intracerebroventricular kainic acid. In 55% of the cells studied orthodromic excitation evoked bursts of action potentials. This bursting activity was associated with a