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Spontaneous Vesicle Formation in Aqueous Solutions of Comb-Like PEG

✍ Scribed by Xiaolin Li; Jian Ji; Jiacong Shen

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
194 KB
Volume
27
Category
Article
ISSN
1022-1336

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✦ Synopsis

Abstract

Summary: A novel comb‐like poly(ethylene glycol) (CPEG), with dominant water‐soluble PEG, is found to spontaneously aggregate into vesicles above a certain concentration in water. The hollow, three‐dimensional structure of the vesicles is proven by TEM, SEM, and AFM. The diameters of the vesicles are from 200 to 500 nm with 50 nm walls. The spontaneously formed vesicles can be further cross‐linked by the reaction between divinyl sulfone (DVS) and the hydroxy groups in the side chains of the CPEG. The spontaneously formed vesicles with dense reactive hydroxy groups will have great potential in both applications and research.

SEM image of the uncross‐linked vesicles.

imageSEM image of the uncross‐linked vesicles.

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