Significant differences in the dispositi
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Bianca M. Liederer; Kimthoa t. Phan; Hui ouyang; Ronald T. Borchardt
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Article
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2005
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John Wiley and Sons
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English
โ 177 KB
The stabilities of DADLE ([D-Ala2,D-Leu5]-Enk, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH), the capped derivative Ac-DADLE-NH2, and the oxymethyl-coumarinic acid (OMCA)-based cyclic prodrug of DADLE and [D-Ala2,Leu5]-Enk (H-Tyr-D-Ala-Gly-Phe-Leu-OH) were determined at 37 degrees C in rat and guinea pig liver micr