Spontaneous recurrent mutations and a complex rearrangement in the MECP2 gene in the light of current models of mutagenesis
β Scribed by Tihomir Todorov; Albena Todorova; Cristina Motoescu; Petia Dimova; Daniela Iancu; Dana Craiu; Daniela Stoian; Ligia Barbarii; Veneta Bojinova; Vanyo Mitev
- Book ID
- 113809652
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 456 KB
- Volume
- 734
- Category
- Article
- ISSN
- 0027-5107
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Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder that manifests as varying combinations of tumors of endocrine and other tissues (parathyroids, pancreatic islets, duodenal endocrine cells, the anterior pituitary and others). The MEN1 gene is on chromosome 11q13; it was re