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Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix†

✍ Scribed by Hunt, John F.; Rath, Parshuram; Rothschild, Kenneth J.; Engelman, Donald M.


Book ID
115449822
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
478 KB
Volume
36
Category
Article
ISSN
0006-2960

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## Abstract Low‐energy conformations of the S‐peptide fragment (20 amino acid residues long) of ribonuclease A were studied by Monte Carlo simulated annealing. The obtained lowest‐energy structures have α‐helices with different size and location, depending distinctively on the ionizing states of ac