Spontaneous openings of large and small conductance acetylcholine receptor channels in Xenopus myocytes
β Scribed by Rojas, L.; Zuazaga, C.
- Book ID
- 122730844
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 367 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0304-3940
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Single-channel activity was recorded from cell-attached patches on skeletal muscle cells isolated from wild-type mice and from mice carrying the dy or mdx mutations. Spontaneous openings of the nicotinic acetylcholine receptor channel (nAChR) were detected in virtually all recordings from either dyl
During the development of mammalian muscle the ~-subunit of the nicotinic acetylcholine receptor (AChR) is replaced by the e-subunit to produce well-defined alterations in the conductance and gating of the channel. To gain a better unterstanding of the functional role of the V-and e-subunits, we hav