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Spontaneous mutation in familial adenomatous polyposis

โœ Scribed by Rudolph B. Rustin; David G. Jagelman; Ellen McGannon; Victor W. Fazio; Ian C. Lavery; Frank L. Weakley


Book ID
112679112
Publisher
Springer
Year
1990
Tongue
English
Weight
369 KB
Volume
33
Category
Article
ISSN
0012-3706

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Familial adenomatous polyposis (FAP) is a dominantly inherited familial cancer syndrome characterized by an increased predisposition to colorectal cancer and other benign and malignant extracolonic lesions. FAP has been linked to germline mutations of the adenomatous polyposis coli (APC) gene that e