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Spontaneous malignant transformation of a human monocytic cell line, CM-S

✍ Scribed by Revoltella, R.P.

Book ID
123583774
Publisher
Elsevier Science
Year
1985
Weight
105 KB
Volume
21
Category
Article
ISSN
0277-5379

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CM-SM is a clonal line of human precursor mononuclear phagocytes inducible to macrophage differentiation in response to the tumor promoter phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate (TPA). Untreated CM-SM cells contain single class, high-affinity (K, = 4.0 x 10' M) glucocorticoid-specific r