Spontaneous Formation of the Bioactive Form of the Tuberculosis Drug Isoniazid
β Scribed by Martin Wilming; Kai Johnsson
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 97 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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## Abstract Quantifying the relative energy of a ligand in its targetβbound state (i.e. the bioactive conformation) is essential to understand the process of molecular recognition, to optimize the potency of bioactive molecules and to increase the accuracy of structureβbased drug design methods. Th