Spontaneous expression of fra(10)(q25) in bone marrow from a patient with agranulocytosis

Increased interleukin-18 expression in b

Increased interleukin-18 expression in bone marrow of a patient with systemic juvenile idiopathic arthritis and unrecognized macrophage-activation syndrome

✍ Nobuaki Maeno; Syuji Takei; Hiroyuki Imanaka; Kimie Yamamoto; Kazumi Kuriwaki; Y 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB 👁 2 views

## Abstract The aberrant induction of proinflammatory cytokines is considered to be crucial in the pathogenesis of systemic juvenile idiopathic arthritis and adult‐onset Still's disease. Interleukin‐18 (IL‐18) in particular has been reported to be a candidate for the key cytokine in both diseases;