SPONTANEOUS END-PLATE ACTIVITY IN NORMAL SUBJECTS AND IN PATIENTS WITH MYASTHENIA GRAVIS
โ Scribed by David Grob
- Book ID
- 114879347
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 1003 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0890-6564
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๐ SIMILAR VOLUMES
## Abstract In order to evaluate the mechanisms of weakness in muscles of patients with myasthenia gravis (MG), intercostal muscle biopsies were obtained from 9 normal subjects and 6 MG patients, and the compound muscle action potential (AP) and tension responses to nerve and muscle stimulation, an
In myasthenia gravis, loss of acetylcholine receptors at motor end-plates is induced by antireceptor autoantibodies. At end-plates in rats in which myasthenia gravis-like symptoms are induced by chronic treatment with a-bungarotoxin, acetylcholine release is increased. Within muscles from such rats